The collapse of Israel-Turkey relations over the last decade has led to a reshuffling of the power plays in the East Mediterranean region. Following the dismantlement of the Ankara-Jerusalem axis, Greece has entered the game by becoming the new ally of Israel in the area. As a result, the new strategic triangle that emerges in the region has implications at both the security and economic levels. Its future will shape not only the regional security system but also the prosperity of the area, for instance by defining the governance of energy discoveries. Therefore, it will have direct implications for the U.S. security interests.