A healthy Latin America is of critical value to the United States as a global power. It is besieged by a powerful force of resentment engendered by a combination of weak states, social exclusion, criminal violence, and corruption. In the context of attack by radical populism against democratic values, the United States needs a new grand strategy that addresses the causes rather than the symptoms of the malaise. The author argues that such a strategy must strengthen the effectiveness of the democratic state in providing security, justice, and governance, as well as effectively engender a linkage of the 40 percent of the population presently excluded from the social and economic benefits of democracy to the national and international economy. Unless current trends reverse, Latin American countries will be poor security partners and a continuing menace for international security. The author recommends imaginative courses of action for the grand strategy.